Staying mid air when fighting her is very helpful, as you can dodge her projectile weapon attacks.

At the start of each round, you can use your first setback at her, sending her way back and having her walk across a big path without any movement ability. If she plays Mother's Grace, act quickly, before she goes into cc immune state.

You can actually challenge Makoa, because you can ult to execute him, as he does not become untargetable to your ult while in ancient rage.

Atlas Shield shuts down Skye's Ult completely, so try to read her mind and time it correctly when u believe she has her Ult ready.