Avoid stacking up in a line as you attack or your team will get speared with a presence shot for 800 piercing damage. Be wary if you see a Lian with Eminence as it will focus on presence spam. Stay behind shields as it cancels on hit effects.
Lian, contrary to most damage dealers, is food for most tanks. An aggressive tank like Fernando or Ash essentially have her on a guaranteed death timer the moment they press F, and defensive tanks like Barik and Ruckus outdps and destroy her.