Always throw a Dead Zone on Planted Yagorath, as it will most likely force her to retreat.

When Tiberius does his ult and jumps in the air, you can void grip him to break his immunity and have your teammates kill him.

Go chain reaction and spam your bombs on her. The extra damage can devastate her.

Debilitate Skye bursts Yagorath down quickly, especially if you have a Tank Burner built for her.