Strix's stealth can make him harder to track, so toss your Sensor Drones out where you expect him to be and reveal him to your team. If you run the Booby Trap talent, the explosion of your drones can disrupt his aim or throw him off of high ground.
Assuming you don't have more important targets, hold your ult for when Vivian uses hers. Tag her with a bit of damage, then ult. Be wary of supports being nearby, or if she's running the Scapegoat card, as either will likely shut down the kill
If you have several totems down and Willo hits you with Dead Zone, you can use your Ghost Walk to briefly cleanse the effect and continue to heal yourself.
With the Treacherous Ground talent, you can prevent Grohk from using his Ghost Walk. With moderate levels of anti-healing, you can potentially kill him even through the healing of his totems.