Makoa's Dredge anchor will ignore Reversal entirely so you cannot rely on it. You can, however, hide behind walls and geometry and peek to perform one shot at a time, forcing Makoa to eventually retreat due to poke damage.
Keep an eye on whether or not Androxus is using the Dark Stalker legendary card. If not and you know Nether Step is on cooldown, Makoa can use Dredge Anchor and Androxus will not be able to Nether Step away.
When using Androxus, its always good to be near the Makoa with your revolver. When Makoa attacks up front you need stay close to him but on the sides. As soon as you see him use his shield you must dash straight away and use your punch to finish him.