In a general way, avoid character who is able to do big damage in a single shot, you will often loose unless they are already low.

When you face Makoa on a map whith "fall" space, beware of his anchor, as a skilled player will often push you over the edge.

Bomb king is a burst type character, beside your anchor, avoid the fight or have a heal to support you.

Try to be close to her but aim for her mines first so you aren't a target too easy, thunder can also be good to deal whith those, if you are far from her stay out of her line of sight as you are an easy target, keep healing your team instead