Maeve has a particularly harder time than most champions with aiming, as her weapons have drastic gravity drop, and have projectile speed, which means moving around unpredictably will make yourself harder to kill.
Heroes who have a card that allows them to reveal enemies with weapon shots are extremely strong against Skye. For example, Viktor's Predator card allows him to reveal targets for half a second every time they get hit by Iron Sights.
Force an Androxus into a long range fight. For example, if you are playing Kinessa, and an Androxus sneaks up behind you, teleport to a distance, and open fire from there. He will either have to fight if he does not have Nether Step or run.
Sha Lin's basic attack an Planted Ability easily shred through his shield, and allows Sha Lin to easily kill Fernando. Additionally, with Wrecker, his shots deal even more damage, which easily melts Fernando's shield like butter.