When an Androxus activates Reversal and you have fired to much already, dodging around makes you a much harder target to hit. Also, if you want to deal damage, and you have an AoE attack ability, aim slightly in front or to the side to hit him.
It's highly probable that Androxus will Refersal and then Nether Step away from combat when in danger. After that, he's mostly a sitting duck, because you probably still have your movement abilities and he doesn't.
While Androxus is channeling Reversal, take the time to reload your weapon, switch targets for a moment, or escape if needed, as it's detrimental to you to attack him during this time.