Flank/Damage pip is not as vulnerable as other builds use more caution when approaching him he has high burst damage and a heal. if your going to flank him try to wait till he shootsthe catalyst on someone else to give your self an edge.
Furia is a high damage healer mostly for her pyre strike. this can seal kills and stop flankers in their tracks but it takes a long time to spawn just attacking her can bait her to use it and juke her out and seal the kill.
Exterminate can be really mean if furia has the stun duration boosted almost killing non frontline champions with the damage dealt during the stun alone. getting Resilience will shorten this stun Giving you the chance to excape.