Skye is extremely squisy. Try to stay as sneaky as you can. Also avoid AOE champions as much as you can because they can still hit you even if they are not aiming at you.
Sticky Bombs removed from champion, if he\she uses movement skill.
Inara doesn't have any movement skills. So use "Chain reaction" legendary versus Inara.
With good aim you can kill her with 3-5 Sticky Bombs.