If you can land a Pyre Strike on Talus when he's approaching half health, you can keep him from manually returning to his Rune of Travel and give you and your team time to finish him off.

A good tip is if you run Faustian Bargain, you can technically bait Furia into trying to kill you, then let it run out, use it again, behind her, and hit your abilities on her, and it would be a free kill.