Khan's ultimate relies on line of sight to grab his desired target, pull up Fernando's Shield and block your allies with it. Khan cannot grab any targets behind Fernando's Shield unless he has already fired his ultimate.
Inara with Treacherous Ground will murder your whole team if you are not careful. She can trap multiple champions, allowing teammates to decimate them, and she can dish out some damage too. Consider taking Bulldozer just to destroy Warder's Field.
Found Talus' Rune? Booby trap it! That champion makes a distinctive sound when teleporting back, use it as an audio cue even when you step back from it to know when to explode your bombs.
Grumpy Bomb combined with Demolition legendary is a nightmare for Barik, especially if he's with another front liner. That's because he likes to set himself up in one place, and you are forcing him out every 10 seconds.
If you see Terminus with Seris run for your life because that's a fight you cannot win the best strategy is to either lure seris away from terminus or kill her without terminus even knowing cause he'll try to block all your shots letting her escape