Chronos. There is rarely a reason to get anything else for Jenos except Chronos if you're intending to heal with him. If you find yourself being hard-countered get Chronos II then buy another item to properly defend yourself.
Jenos' healing is independent of his location. Expect him to flank your team while still healing his. If he tries to run away, don't try to chase the kill as he can waste time but instead scare him away from his team, lest he support in hiding
Jenos actually an off combat healer since he can heal through walls and trying to not exposed.try to find Jenos behind a solid cover or at the place where champions can hide safely and then try outflank him