Mainly when going up against Skye, you'll be already halfway below health because she has surprised you. In that case use Withdrawal to counter. If you feel like you're ready, or Skye is about to disappear, use Planted to shred her down.
Dredge may have good long range damage but he is very bad at dealing with flanks up close. It's best if he doesn't see you flanking him so a champion such as Skye is best.
Inara is a time sink for you because she has too much health and damage mitigation. Though you still counter her because Inara is weak at long range and she's not mobile enough to chase you down.